Batf3 ko
웹2024년 5월 1일 · Batf3 knockout mice were purchased from Jackson Laboratory. SB1 cells were generated by the Gores laboratory ... KO, knockout; PD-1, programmed cell death 1. (This figure appears in color on the web.) Addition of anti-CD40/PD-1 enhances response to chemotherapy in mice with advanced iCCA. 웹The role of different DC subsets in priming and maintenance of immunity against Leishmania major (L. major) infection is debated. The transcription factor basic leucine zipper …
Batf3 ko
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웹Additional monocyte-derived cells (MCs) with DC-like properties (moDCs) can be generated during pathogen-initiated inflammation via the differentiation of monocytes [ 6 ]. Figure 2. … 웹한 연구에서는, CD8α + DC 발달에 관여하는 basic leucine zipper ATF-like transcription factor (BATF) 3를 제거한 BATF3 knockout (KO) 마우스에서는 CD8α + DC가 발달하지 않으며 종양 내 항암 면역 반응이 저해되어 있음을 확인하였다.
웹品系名： C57BL/6JSmoc- B2mem3Smoc. 品系状态 ：活体 目录号：NM-KO-18021. 应用领域： 免疫系统. 小鼠. 웹Furthermore, we found this combination strategy to be dependent on cDC1s, and its therapeutic efficacy to be abrogated in cDC1-deficient Batf3−/− mice. Thus, we demonstrated that the adjuvanticity of dMMR CRCs can be improved by combining low-dose chemotherapy and oncolytic HSV-1 in a cDC1-dependent manner.
웹2012년 9월 19일 · Intracellular pathogens or IL-12 restore lymphoid CD8α + cDCs and tissue-resident CD103 + cDCs in Batf3 −/− mice. a, Wild type (WT) and Batf3 −/− (BATF3 KO) 129SvEv mice were uninfected (CTL) or infected with Mtb, and spleens harvested and analyzed by FACS at the indicated time. Histograms for indicated markers are gated as … 웹2024년 6월 9일 · RIPK3-dependent signaling induced by MF59 or AV was essential for cross-presentation of antigen to CD8 T cells by Batf3-dependent CD8 ... Batf3 KO and Caspase 1 KO mice were purchased from Jackson ...
웹복강 DC subset 형성에 영향을 미치는 사이토카인 및 전사인자의 관련성을 분석하기 위해 2종의 사이토카인들(Flt3L, GM-CSF)을 각각 마우스에 주입 후 복강 DC subset별 생성 차이를 …
웹2024년 4월 2일 · SemmrichfiM eal unher ancer 202410e003488 doi101136jitc-2024-003488 1 Open access Vectorized Treg- depleting αCTLA- 4 elicits antigen cross-presentation and CD8+ T cell immunity to reject ‘cold’ tumors Monika Semmrich,1 Jean-Baptiste Marchand,2 Laetitia Fend,2 Matilda Rehn,1 Christelle Remy,2 Petra Holmkvist,1 Nathalie Silvestre,2 … limits of language bss웹Batf3-ko and C57BL/6-mice were infected i.v. with 4 × 106 infectious particles of HSV. Mice were sacrificed 5 days later and spleens were analyzed for presence of HSVgB-specific … limits of infinitely nested radicals웹2024년 1월 16일 · Batf3 KO mice lack alloresponse We previously investigated antigen cross-priming by immunizing B6 mice (H-2b) intraperitoneally (i.p.) with irradiated allo-cells (H-2d) expressing the highly immunogenic simian virus 40 large T antigen (D2.SV cells), which immortalizes the cells. Infecting cells with influenza A virus (IAV) to generate an ... limits of integration change웹2024년 7월 1일 · BATF3 KO mice, which specifically lack CD8 + and CD103 + DCs, are unable to exhibit competent tumor-specific cytotoxic T cell immunity. Alternatively, CD8 + T cells were depleted by intraperitoneal injection of a neutralizing antibody. limits of informed consent웹2024년 9월 26일 · 此外，研究人员对batf3进行了全基因组的结合测试，即batf3 chip试验，并确定了batf3能结合到自身的启动子位点上并产生一种正反馈的回路；当研究者 ... limits of instant runoff웹2024년 3월 29일 · Sultan H, Wu J, Kumai T, Salazar AM, Celis E. Role of MDA5 and interferon-I in dendritic cells for T cell expansion by anti-tumor peptide vaccines in mice. Cancer Immunol Immunother. 2024 Jul;67(7):1091-1103. doi: 10.1007/s00262-018-2164-6. Epub 2024 Apr 25. limits of insurance 意味웹2024년 6월 12일 · BATF3-dependent CD103 + DCs of the GI tract are better known for their potency at driving CD8 + T cell immunity [3, 34, 35] and for their role in priming Treg differentiation through the production of retinoic acid [36, 37]. Our data, as well as the results from the Leishmania and Tritrichomonas musculis studies , further ... limits of human survival