WebPatients with high tumor burden (CHAARTED high-volume and/or LATITUDE high-risk) were evaluated in this study. We identified 67 and 135 patients in the ADT/CAB and … WebNational Center for Biotechnology Information
Final CHAARTED data now published in NEJM THE "NEW
WebDec 1, 2024 · CHAARTED In the CHAARTED trial (Chemo Hormonal Therapy Versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer), metastatic hormone-sensitive prostate cancer (mHSPC) patients with high-volume disease (HVD) particularly benefited from combined chemohormonal treatment ( 1 ). WebFeb 3, 2024 · Results: Median age and prostate-specific antigen level were 73 years and 266.2 ng/ml, respectively. Median OS was 55.5 months in patients who met the CHAARTED high criteria (vs 33.1 months in... sharon kurfuerst christiana care
How many bone metastases may be defined as high‐volume …
WebThis study included 85 patients with CT-based CHAARTED-low volume disease and 20 CT-based CHAARTED-high volume disease. A PSMA-tumor volume of ~40 ml was the optimal cutoff between CT-based CHAARTED-low volume disease (non-unifocal) and high volume disease (non-M1c), with an AUC of 0.86. WebFor example, the CHAARTED trial defined high volume disease as the presence of visceral metastases and/or ≥4 bone lesions with ≥1 lesion beyond the vertebral bodies and pelvis. This study revealed the survival benefit of the upfront use of docetaxel only existed in mPC patients with high volume disease but not in those with low volume ... WebDefinition of high and low volume, and risk in CHAARTED [54-56] and LATITIDE [57] based upon imaging with bone scan and CT scan. Source publication EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate... pop up camper power lift system