Cisplatin s1166
WebApr 1, 2024 · Cell cultures were continued for 48 h after treatment with the indicated cisplatin doses or irradiation. For drug treatment, the cells were cultured 48 h after treatment with indicated cisplatin (S1166, selleckchem) doses. The radiation was done by using Faxitron Multirad 350. Western blot WebNov 12, 2024 · Proline/arginine-rich end leucine-rich repeat protein (PRELP) is a member of the small leucine-rich proteoglycan family of extracellular matrix proteins, which is markedly suppressed in the majority of early-stage epithelial cancers and plays a role in regulating the epithelial–mesenchymal transition by altering cell–cell adhesion.
Cisplatin s1166
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WebMar 20, 2024 · Cisplatin (CDDP) is a platinum-based antitumor drug [ 1 ]. Its widespread use in the treatment of breast cancer, ovarian cancer, and other cancers has greatly improved the survival rate of patients [ 1 – 4 ]. However, this process is often accompanied by serious side effects, including nephrotoxicity and ototoxicity [ 5 ]. WebMay 9, 2024 · Glutathione peroxidase 4 (GPX4) is a key regulator of ferroptosis where it utilizes reduced glutathione to convert lipid hydroperoxides to lipid alcohols, which mitigate lipid peroxidation and...
WebChemicals Hederagenin (A0423) and paclitaxel (A0177) were pur- chased from Chengdu Must Bio-Technology (Chengdu, China); Cisplatin (S1166), bafilomycin A 1(S1413), and N- acetyl-L-cysteine (NAC,... WebJan 24, 2024 · Cisplatin induces dysregulation of GSH metabolism in the renal tubules. (A) The enriched signaling pathways in cisplatin-induced kidneys using KEGG analysis, …
WebJul 16, 2024 · TBK1 inhibitor MRT67307 (S7948), BX-795 (S1274) and cisplatin (S1166, for in vitro experiments) were purchased from Selleck (Houston, USA). Cisplatin (for in vivo experiments) was obtained from Qilu Pharmaceutical (Shandong, China). Anti-Flag M2 agarose beads (M8823) and herring testes (HT) DNA (D6898) were purchased from … WebDec 1, 2024 · It has been discovered that Btz exhibited pleiotropic effects on the treatment of myeloma through targeting DNA repair, cell cycle regulation, unfolded protein response, and apoptotic and classic stress response pathways including caspase-9–mediated intrinsic and caspase-8 (CASP-8)–mediated extrinsic cell death cascades ( Chauhan et al., 2005 ).
WebJun 17, 2024 · Cisplatin is an effective chemotherapeutic drug used for various solid tumors; however, AKI associated with cisplatin treatment limits its clinical usage [ 3 ]. High concentration of...
WebCisplatin (cisplatinum, cis-diamminedichloroplatinum II, CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts in tumor … chippy blackburnWebFeb 21, 2024 · The resistant cell line DLD1 was established in vitro by intermittent exposure to different concentrations of cisplatin (S1166, selleck) in stepwise increments of time. … grape shaped bodyWebCisplatin (NSC 119875, Cisplatinum, cis-diamminedichloroplatinum II, CDDP, cis DDP, DDP) is an inorganic platinum complex, which is able to … chippy blackwood deskWebApr 1, 2024 · Cisplatin is combined with radiotherapy for advanced head and neck squamous cell carcinoma (HNSCC). While providing a beneficial effect on survival, it … chippy birdWebALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Application of stem cell biology to breast cancer research has been limited by the lack of simple methods for identification and isolation of … chippyblossomWebcisplatin: [noun] a platinum-containing antineoplastic drug Cl2H6N2Pt used especially in the treatment of testicular and ovarian tumors and advanced bladder cancer. grape shaped mugsWebUpon either expressing wild-type TRAF6 (fig. S2A) or treating cells with various chemotherapeutic DNA-damaging drugs, including etoposide, doxorubicin, or cisplatin ( … grape shaped mugs marked s.s. c