Ctcf和ctcfl

WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is … WebJan 5, 2024 · CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia followed by age-dependent cell death in the excitatory neurons …

CTCF and CTCFL in cancer - ScienceDirect

WebMar 29, 2024 · CTCFL regulates the PI3K-Akt pathway and it is a target for personalized ovarian cancer therapy. Transcription Factor CTCFL Promotes Cell Proliferation, … WebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they termed BORIS. The deduced 663-amino acid protein contains 11 central ZFs, like CTCF, but it has unique N and C termini. EMSA analysis showed an interaction with testis DNA. ionix hair mask https://traffic-sc.com

Defining the relative and combined contribution of CTCF …

WebCTCF-mediated enhancer blocking is conserved from Drosophila to man (Moon et al. 2005) Antisense transcription of triplet repeats is constrained by CTCF (Cho et al. 2005) Boundaries between X inactivation and escape of inactivation bind CTCF (Filippova et al. 2005) CTCF antagonizes with CTCFL at the cancer testis gene MAGE-A1 (Vatolin et al. … WebApr 1, 2024 · CTCF and CTCFL contain N-terminal and C-terminal domains and a central 11-zinc finger region. CTCF binds to approximately 80 000 sites on mammalian chromosomes [33,34] through a subset of its eleven zinc fingers (ZFs). The ZFs of CTCFL and CTCF have significant homology with the ZFs of CTCF (74.1%), but the N-terminal … WebOct 8, 2024 · By PCR screening a testis cDNA library for CTCF-like sequences, followed by 5-prime RACE, Loukinov et al. (2002) isolated a cDNA encoding CTCFL, which they … on the allotment

Molecular basis of CTCF binding polarity in genome folding

Category:The combined action of CTCF and its testis-specific …

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Ctcf和ctcfl

Anti-CTCF Antibody serum, Upstate® Sigma-Aldrich

WebWidespread expression of BORIS/CTCFL in normal and cancer cells. BORIS (CTCFL) is the paralog of CTCF (CCCTC-binding factor; NM_006565), a ubiquitously expressed …

Ctcf和ctcfl

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WebMay 11, 2024 · Ubiquitously expressed CTCF is involved in numerous cellular functions, such as organizing chromatin into TAD structures. In contrast, its paralog, CTCFL, is normally only present in the testis. However, it is also aberrantly expressed in many cancers. While it is known that shared and unique zinc finger sequences in CTCF and CTCFL … WebSep 3, 2024 · The putative ORFs of these shark CTCFL genes, as well as their CTCF genes (Supplementary Data 1), were all revealed to possess eleven zing finger domains, as known for CTCF and CTCFL genes of ...

WebCTCF is listed in the World's largest and most authoritative dictionary database of abbreviations and acronyms CTCF - What does CTCF stand for? The Free Dictionary WebApr 4, 2024 · Title: CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming. Myotonic dystrophy type 1 …

WebApr 1, 2024 · CTCF plays a key role in organizing chromatin into TAD structures but it can also function as a transcription factor. CTCFL (CTCF-like), the paralog of CTCF, is … WebCTCFL Antibodies. Antibodies that detect CTCFL can be used in several scientific applications, including Western Blot, Immunocytochemistry, Immunohistochemistry, …

WebMay 11, 2024 · In line with these differences, CTCF and CTCFL have very different expression profiles: CTCF is present in all cell types, while in contrast CTCFL is normally …

WebJun 18, 2012 · CTCFL acts as a male germ cell gene regulator, preferably binding near promoters with active chromatin marks. Interestingly, CTCF and CTCFL bind a highly … on the altar upperroom spanishWebJun 22, 2024 · CTCF is a key organizer of the 3D genome. Its specialized paralog, BORIS, heterodimerizes with CTCF but is expressed only in male germ cells and in cancer states. ionix elk city oklahomaWebSep 3, 2024 · Asymmetric expression patterns between shark CTCF and CTCFL. To examine possible commonalities of expression patterns with mammals, we analyzed … ont health and safety actWebApr 10, 2024 · CTCF (CCCTC-binding factor)是一种重要的染色质架构蛋白,其与绝缘子的方向性结合在哺乳动物基因组三维空间结构形成和维持中起着至关重要的作用。. 正向-反 … on the altar upper room chordsWebFeb 7, 2024 · In this case, we also found previously validated targets of CTCFL (Supplementary Fig. 3a, b), such as TGFB1 31, FN1 7, and the H19 gene, which has been widely studied as a target of CTCFL and CTCF ... on the altarWeb我们为您找到 ctcf 的 1 个相关产品结果。 ... 生命科学基础与转化研究的主要领域，包括细胞生物学、肿瘤、免疫与炎症、表观遗传学和转录调控、代谢与内分泌、衰老、心血管、干细胞和发育、神经科学、蛋白质翻译后修饰等，还提供病理学研究与伴随诊断 ... on the alpsWebU25435 - Human transcriptional repressor (CTCF) mRNA, complete cds. BC130486 - Homo sapiens CCCTC-binding factor (zinc finger protein)-like, mRNA (cDNA clone MGC:163358 IMAGE:40146517), complete cds. DQ294738 - Homo sapiens BORIS-like protein (CTCFL) mRNA, complete cds, alternatively spliced. BC014267 - Homo sapiens CCCTC-binding … on the altar lyrics upperroom