WebJul 25, 2002 · The rationale for selecting the axonemal heavy chain dynein 11, DNAH11, gene is fourfold. First, various chains of axonemal dyneins are structural components of the dynein arms ( 6 ) within the ciliary microtubular structures of respiratory epithelia and sperm cells; these arms are often absent or defective in PCD patients ( 5 ). WebDNAH14 (dynein, axonemal, heavy chain 14), also known as C1orf67 or HL18, is a 3,507 amino acid member of the dynein heavy chain protein family. DNAH14 is one of the force generating protein of respiratory cilia and may be involved in sperm motility through sperm flagellar assembly.

Dynein - Wikipedia

WebMay 1, 2001 · The dynein heavy chain is enormous, being approximately 4600 amino acid residues in length, more than twice the size of myosin II and more than four times the mass of conventional kinesin. Unlike myosin and kinesin, the predicted secondary structure of the dynein sequence does not readily divide into a globular head and a tail domain. WebRefSeq Summary (NM_001145154): Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. Two major … chucky season 3 update

Rare variants in dynein heavy chain genes in two individuals with

WebMay 1, 2024 · In individual 2, one rare variant (c.9110A > G;p.(H3037R)) in the dynein axonemal heavy chain 11 gene (DNAH11), coding for another component of the outer … WebCytoplasmic dynein, which has a molecular mass of about 1.5 megadaltons (MDa), is a dimer of dimers, containing approximately twelve polypeptide subunits: two identical "heavy chains", 520 kDa in mass, which contain … WebDynein axonemal heavy chain 11 (DNAH11), is a protein that is encoded by the DNAH11 gene in humans. In mice, the protein is known as Dnahc11 and is encoded by the murine Dnahc11, the murine homolog to human DNAH11.The protein is also known as 'left-right' dynein (lrd) and is particularly notable during embryogenesis. chucky season 3 tiffany