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Fzd10 antibody

WebAnti-FZD10 ADCC Enhanced Antibody (OTSA101) is an ADCC enhanced antibody produced by our Afuco™ platform. OTSA101 is an antibody drug targets a novel tumor-specific antigen FZD10 (Frizzled homolog 10), used for cancer therapy, has conducted phase I clinical trial for synovial sarcoma, which is a type of soft tissue sarcoma. ‹ › WebAnti-FZD10 Rabbit Polyclonal Antibody (Cy5®) VWR. Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes.

anti-FZD10 antibody (AA 101-200) Product No. ABIN1714166

WebHuman Frizzled-10 Antibody Summary Species Reactivity Human Specificity Detects human Frizzled-10 in direct ELISAs. Source Monoclonal Mouse IgG 2B Clone # 1023101 Purification Protein A or G purified from cell culture supernatant Immunogen Mouse myeloma cell line, NS0-derived human Frizzled-10 Ile21-Gly161 Accession # Q9ULW2 … WebFrizzled 10/CD350 Antibody (BS-13216R) in IHC (P) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-Frizzled 10/CD350 Polyclonal Antibody, Unconjugated (bs-13216R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Product Details Target Information cheap school online traffic school https://traffic-sc.com

FZD10 antibody Immunohistochemistry HPA014484 - Sigma-Aldrich

Web(18175-1-AP) Frizzled 10 antibody Sign in or register to save this reagent to your favourites Supplier Proteintech Host Rabbit Type Primary Clonality Polyclonal Conjugate Unconjugated Target Frizzled homolog 10 (Drosophila) (Human) UniProt Q6NSL8 - Q6NSL8_HUMAN Gene FZD10 View Product On Supplier's Website Request a Quote from Proteintech Web上海康朗生物科技有限公司主要致力于“Anti-acetyl Lysine抗体”的生产销售。多年的“Anti-acetyl Lysine抗体”生产与销售的经验，与各行业新老用户建立了稳定的合作关系，我公司经营的产品名称深受广大用户信赖。欢迎来电咨询或前来选购。 联系电话：021-61998208。 Web公告提醒：爱必信所有产品和服务仅用于科学研究，不用于临床应用及其他用途提供产品和服务（也不为任何个人提供产品和服务）! 抗体描述： 产品名称：Rabbit anti-BMPR2 Polyclonal Antibody 产品别名：BMPR2抗体 宿主：Rabbit 反应种属：Hum cybersecurity csm

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Category:Afuco™ Anti-Human FZD10 ADCC Recombinant Antibody …

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Fzd10 antibody

FZD10 antibody Immunohistochemistry HPA014485

WebParaffin-embedded human colon tissue stained for FZD10 using ab254588 at 1/20 dilution in immunohistochemical analysis. Immunocytochemistry/ Immunofluorescence - Anti … WebDec 12, 2024 · Deriving FZD10 binder from a template antibody The Wnt signaling pathway is initiated by Wnt binding to the extracellular cysteine-rich domain (CRD) of FZD receptors. The 10 FZD CRDs share almost identical fold and surface features, which are the key reason for the pleiotropic effects of Wnt ligands.

Fzd10 antibody

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WebProduct name Anti-FZD10 antibody See all FZD10 primary antibodies Description Rabbit polyclonal to FZD10 Host species Rabbit Tested applications Suitable for: ICC/IF, IHC-P more details Species reactivity Reacts with: Human Immunogen Recombinant fragment corresponding to Human FZD10 aa 450-550. Database link: Q9ULW2 Run BLAST with … WebThis antibody was able to induce ADCC of synovial sarcoma cells in vitro and inhibited the growth of tumor xenografts in vivo. This group later developed an anti-FZD10 mAb (MAb 92-13) by immunization of mice with FZD10-overexpressing COS cells and screening hybridoma supernatants with whole cell ELISA ( Fukukawa et al., 2008 ).

WebThe following primary antibodies were used: anti-FTO (abcam, ab126605, ... between FTO and FZD10 expression, (G) between FTO and RASSF6 expression, (H) between FTO and YAP1 expression, and (I) between FTO and TAZ expression based on online data in GEPIA. OS analysis of cervical cancer patients based on (J) BMP4, (K) FZD9, (L) FZD10 and (M ... WebImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FZD10 antibody (ab150564) Immunohistochemical analysis of formalin-fixed, paraffin …

WebThis antibody has been used for staining of 44 normal human tissue samples as well as human cancer samples covering the 20 most common cancer types and up to 12 … WebMar 30, 2024 · We report a first-in-human phase I of monoclonal antibody (OTSA-101) targeting FZD10, overexpressed in most SS but not present in normal tissues, labelled with radioisotopes and used as a molecular vehicle to specifically deliver radiation to FZD10 expressing SS lesions. Methods: Patients with progressive advanced SS were included. …

WebResults for FZD10 antibodies 356 products found Reagent type. Antibodies (356) Experimental Models (9) Kits (5) Proteins (63) Refine your results Clear all. cyber security cs stevensWeb丁香通为您提供CADM1Rabbitp商品详情介绍：价格：￥1580，货号：A1892_100μL，品牌：ABclonal，产地：武汉，详见丁香通CADM1Rabbitp商品详情页； cyber security cssfWebJul 10, 2024 · 그런 다음, 조립된 Fc 유전자 단편 풀을 안티바디 디자인 랩스(Antibody Design Labs)의 pADL-22c 파지미드 벡터의 Sfi 절단-부위로 클로닝하였다. 8×10 10 개 변이체의 실험적 다양성을 생성하기 위해 클로닝된 DNA 라이브러리를 전기천공적격(electrocompetent) TG1 대장균 세포에 ... cheap schools for saleWebFeb 7, 2024 · Frizzled-10 (FZD10) is a 7-transmembrane-type WNT receptor, which is highly expressed in colorectal cancer, gastric cancer, and synovial sarcoma. , , It has been reported that FZD10 activates the classical WNT/β-catenin/TCF signaling pathway in colorectal cancer cells and also the atypical WNT/JNK signaling pathway to enhance … cheap school organizing containersWebApr 8, 2024 · Aberrant Wnt signaling activation is frequently observed in many cancers. The mutation acquisition of Wnt signaling leads to tumorigenesis, whereas the inhibition of Wnt signaling robustly suppresses tumor development in various in vivo models. Based on the excellent preclinical effect of targeting Wnt signaling, over the past 40 years, numerous … cyber security cspWebObjective: Frizzled homolog 10 (FZD10) is expressed at high levels on the cell surface of almost all synovial sarcoma tissues, but is absent in most normal organs. In a previous study, yttrium-90 ( (90)Y)-labeled anti-FZD10 antibody (MAb 92-13) showed considerable therapeutic efficacy in synovial sarcoma cell-bearing mice. cybersecurity csrfWebFZD10/Frizzled-10 is a 581 amino acid protein belonging to the G-protein coupled receptor Fz/Smo family and containing a signal peptide, a cysteine-rich domain in … cheap school polo shirts