WebJun 1, 2004 · The overexpression of Glut1 in human cancers is known to be closely related to 18 F-FDG uptake in PET (10–12), though there is a controversial report ().Several immunohistochemical studies have demonstrated overexpression of Glut1 in human malignancy and a correlation between Glut1 expression and neoplastic progression … WebJun 20, 2024 · Overexpression of LAIR-1 in OS cells inhibits Glut1 expression and may further regulate glucose metabolism, thus inhibiting EMT and OS progression. Conclusions The findings of our study demonstrated that LAIR-1 are overexpressed in human OS tissues and that LAIR-1 expression is significantly higher in the T2 stage OS tumor than in the …
MUC16 promotes EOC proliferation by regulating GLUT1 expression
WebSIRT1 overexpression or GLUT1 overexpression alone was sufficient to promote cell proliferation and glucose uptake in BC cells. EX527, a specific inhibitor of SIRT1, exerted an opposing effect on bladder cancer proliferation and glucose uptake. The effect of EX527 could be partially reversed by GLUT1 overexpression. WebApr 21, 2024 · Cardiac-specific overexpression of Glut1, the embryonic form of constitutively active glucose transporter, resulted in an increase in glucose uptake and concomitant … jed juele
Prognostic significance of genetic variants in GLUT1 in stage III …
WebThis study tested the hypothesis that GLUT-1 is a marker of radioresistance in oral squamous cell carcinomas (OSCC). A GLUT-1 labeling index (LI) was determined by immunohistochemistry in 40 pretreatment OSCC biopsies. Radiation responses were categorized by histopathology of the resection specimens. Associations between the LI … WebJun 20, 2024 · Overexpression of LAIR-1 in OS cells inhibits Glut1 expression and may further regulate glucose metabolism, thus inhibiting EMT and OS progression. … WebJan 31, 2024 · GLUT1 overexpression is related to poor outcomes in various cancers including NSCLC. 10, 11 In a study by Zhao et al 9., GLUT1 significantly upregulated cyclin A, cyclin D1, cyclin E, cyclin dependent kinase 2 (CDK2), CDK4, CDK6, and matrix metalloproteinase 2, but downregulated p53 and p130 in NSCLC cell lines (A549 and … jed kaffe