High affinity copper uptake protein

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August undefined, 2024

Web5 de jun. de 2001 · Copper serves as an essential cofactor for a variety of proteins in all living organisms. Previously, we described a human gene (CTR1;SLC31A1)that encodes a high-affinity copper-uptake protein and hypothesized that this protein is required for copper delivery to mammalian cells. WebCrystal structure of the high-affinity copper transporter Ctr1. PDB DOI: 10.2210/pdb6M97/pdb. Classification: TRANSPORT PROTEIN. Organism (s): Salmo salar, Escherichia coli. Expression System: Komagataella phaffii GS115. Mutation (s): Yes. Membrane Protein: Yes OPM PDBTM MemProtMD mpstruc. Deposited: 2024-08-22 …

High affinity binding between copper and full-length prion protein ...

WebHuman CTR1 is a high-affinity copper transporter that also mediates the uptake of the anticancer drug cisplatin by largely unknown transport mechanisms. Here we report the 6 … Web5 de abr. de 2024 · Ctr1, a high-affinity copper transporter, is a homotrimeric integral membrane protein that provides the main route for cellular copper uptake. Together with … how long can dinnerly sit outside

O15431 - UniProt

WebProtein target information for High affinity copper uptake protein 1 (Norway rat). Find diseases associated with this biological target and compounds tested against it in … WebGene ID: 102804936, updated on 5-Feb-2024. Summary Other designations. high affinity copper uptake protein 1-like Web15 de mar. de 1996 · Two proteins in the plasma membrane of yeast—a multicopper oxidase, encoded by the FET3 gene, and a permease, encoded by the FTR1 gene—were shown to mediate high-affinity iron uptake. FET3 expression was required for FTR1 protein to be transported to the plasma membrane. how long candles burn

6M98: Crystal structure of the high-affinity copper transporter …

Characterization of the Saccharomyces cerevisiae High …

WebLOC108023471 high affinity copper uptake protein 1 [] Gene ID: 108023471, updated on 15-Oct-2024. Summary Other designations. high affinity ... WebWe ascertain the ability of these proteins to functionally complement and transport copper in the corresponding Saccharomyces cerevisiae high-affinity copper transport mutant. The specific expression pattern of the Arabidopsis COPT1–5 mRNA in different tissues was analyzed by RT-PCR. how long can diverticulitis lastWeb21 de mar. de 2024 · High Affinity Copper Uptake Protein 1 3 4 Copper Transporter 1 3 4 Solute Carrier Family 31 (Copper Transporters), Member 1 3 Copper Transport 1 Homolog 3 External Ids for SLC31A1 Gene HGNC: 11016 NCBI Entrez Gene: 1317 Ensembl: ENSG00000136868 OMIM®: 603085 UniProtKB/Swiss-Prot: O15431 Previous HGNC … how long can divorce be dragged out for

"Web1 de out. de 2002 · High affinity copper uptake protein 1 Gene Slc31a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 196 Protein … " - High affinity copper uptake protein

High affinity copper uptake protein

Slc31a1 solute carrier family 31, member 1 [ (house mouse)]

Web5 de jan. de 2024 · high affinity copper uptake protein 1, copper transporter 1, solute carrier family 13 (sodium/sulphate symporters), member 1 GeneRIFs: Gene … Web11 de mai. de 2024 · At physiological pH, NGF peptides bind one equivalent of copper ion with higher affinity of Aβ and lower than hCtr1 peptide fragments. Therefore, in the …

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WebHigh affinity copper uptake protein 1 DrugBank Online with DrugBank on your side. High affinity copper uptake protein 1 Details Name High affinity copper uptake … Web27 de abr. de 2024 · In silico analysis has revealed three ferroxidase genes, namely CgFET3 (high affinity iron uptake; 70% similarity with ScFET3), ... Rydén, L.G.; Hunt, L.T. Evolution of protein complexity: The blue copper-containing oxidases and related proteins. J. Mol. Evol. 1993, 36, 41–66.

WebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562COPPER (I) IONZINC ION NCBI National Center forBiotechnology Information Search 6M98: Crystal structure of the high-affinity copper transporter Ctr1 in complex with Cu(I) Biological Unit for 6M98: trimeric; determined by author and by software (PISA) High affinity copper uptake protein 1 (CTR1) is a protein that in humans is encoded by the SLC31A1 gene. Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, … Ver mais In 2024, a new autosomal-recessive disease was discovered that is caused by mutations of the CTR1 gene. The disease is characterized by profound deficiency of copper in the central nervous system and presents with … Ver mais • Solute carrier family Ver mais • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". … Ver mais

WebCTR1, high affinity copper uptake protein 1; ATP7A, copper-transporting ATPase 1; CCO, cytochrome C oxidase; ATOX1, copper transport protein ATOX1; KRAS, Kirsten rat sarcoma 2 viral oncogene homolog. Display full size. Figure 1. KRAS-driven colorectal cancer (CRC) cells are addicted to copper metabolism. Webencode a high affinity copper uptake process and was found to be 29% identical at the primary structure level with Ctr1 from yeast. The human protein was, however, substantially smaller than the yeast protein, being composed of 190 amino acids as compared with 406 amino acids (see Fig. 1). hCTR1 is on the

WebHigh CTR1 Expression is associated with poor response to chemotherapy in Muscle-invasive Bladder Cancer. Gene silencing of either CTR1 or DMT1 did not affect copper …

Web15 de abr. de 2024 · High affinity copper uptake protein 1 (pig) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... how long can dog be left aloneWeb27 de mar. de 2024 · The high-affinity Cu transporter Ctr1 (K m ≈ 2 μM) 4, an integral membrane protein localized to the plasma membrane and endosomal vesicles, … how long can dna last on clothingWebHigh affinity copper uptake protein 1 Gene SLC31A1 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 190 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function how long can dnd characters hold their breathWebChimera protein of High affinity copper uptake protein 1 and Soluble cytochrome b562HEXATANTALUM DODECABROMIDEZINC ION. NCBI. National Center for Biotechnology Information. Search. 6M97: Crystal structure of the high-affinity copper transporter Ctr1. PDB ID: 6M97 Download: MMDB ID: 173912: PDB Deposition Date: how long can dogs stay aloneWeb10 de abr. de 2024 · Abstract Heavy metal contamination impacts plant growth and productivity by causing damage at all levels of plant organization, making it one of the most significant abiotic stressors. This study evaluated the uptake and distribution of cadmium (Cd) and copper (Cu) in Solanum lycopersicum L. and identified the antioxidant enzyme … how long can dogs wait to peeWeb1 de abr. de 2014 · As previously mentioned, high-affinity Fe uptake at the plasma membrane depends in S. cerevisiae on Fet3 ferroxidase, which uses Cu as an indispensable cofactor for its activity. Therefore, Cu deficiency leads to impaired Fe transport in yeast, and consequently to multiple Fe-related symptoms [ 61 ]. how long can dogs hold their bladderWebLOC100178573 high affinity copper uptake protein 1-like [ (vase tunicate)] Gene ID: 100178573, updated on 26-Oct-2024. Summary Other designations. high affinity ... how long can divorce take