Ipf scrna
Web15 mei 2024 · Summary. Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease causing alveolar remodeling, inflammation, and fibrosis. We utilized single cell … Web19 jul. 2024 · Rationale: Airway macrophages (AMs) are key regulators of the lung environment and are implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF), a fatal respiratory disease with no...
Ipf scrna
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Web19 aug. 2024 · A hallmark of IPF is alveolar bronchiolization, where epithelial cells express both proximal airway (e.g., SOX2, TP63, KRT5, KRT17, and MUC5B) and alveolar (e.g., … Web12 apr. 2024 · Congratulations to Minxue Jia for the acceptance of his first author Respiratory Research paper, which is entitled “Early events marking lung fibroblast …
WebTo further discover the signature derived from the scRNA-seq of COVID-19 samples, we externally validated the PFB signature in another cohort, comprising 119 idiopathic … Web任意字段 题名或关键词 题名 关键词 文摘 作者 第一作者 机构 刊名 分类号 参考文献 作者简介 基金资助 栏目信息
Web9 mrt. 2024 · Early genetic studies hinted the role of airway epithelial cells in the development of idiopathic pulmonary fibrosis (IPF), while recent single-cell RNA sequencing (scRNA-seq) atlases utilized explant IPF lungs and therefore represent late-stage disease. Web16 mrt. 2024 · 正常肺、IPF肺和hAEC2衍生类器官的组织学比较表明,这些IPF生物标志物优先存在于IPF和hAEC2衍生类器官的基底细胞中,但不存在于正常肺中。 最后,为了确 …
WebWe mapped PAG into IPF scRNA-seq data set GSE135893,8 in which cells derived from biopsies of multiple regions of IPF lung tissues. Thirty-one cell clusters were identified …
Web23 mrt. 2024 · We also found that these IPF subsets had differential expression of pirfenidone-responsive genes suggesting that our findings may ... Rotti PG, Sun X, Yi Y, … devon weather forecast julyWebPF is a clinical phenotype that reflects the end stage of chronic interstitial lung diseases (ILDs) of both known and unknown causes. The most severe form of PF, idiopathic PF … church in chinatown chicagoWebThe Idiopathic Pulmonary Fibrosis (IPF) Cell Atlas (www.ipfcellatlas.com) is a multi-institutional collaboration that seeks to facilitate the exploration of several single-cell RNA … devon weathers ecgWeb8 jul. 2024 · We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung disease, by profiling 312,928 cells from 32 IPF, 28 smoker and … devon wellesley harvey the jamaica gleanerWebscRNAseq to Understand Effects of Drug Treatment for IPF To date, Nintedanib and Pirfenidone are the only approved drugs for treatment of IPF ( 47, 48 ). Two recent … devon what\u0027s onWeb23 mrt. 2024 · GEO help: Mouse over screen elements for information. A comprehensive understanding of the changes in gene expression in cell types involved in idiopathic pulmonary fibrosis (IPF) will shed light on the mechanisms underlying the loss of alveolar epithelial cells, and development of honeycomb cysts and fibroblastic foci. devon weber infectious diseases jeffersonWebScientific Abstract: Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease characterized by airway remodeling, inflammation, alveolar destruction, and fibrosis. We … devon wedding hair and makeup