WebDec 1, 2024 · Objective: To evaluate the safety and exploratory efficacy of intratympanic administration of OTO-313 in patients with tinnitus. Study design: Single intratympanic … WebOTO-313 is a lipid-based formulation of gacyclidine that provides sustained exposure to the cochlea after a single intratympanic injection. Intratympanic delivery of drugs permits deposition over the round window membrane, allowing access to the inner ear for more localized delivery to the cochlea and less systemic drug exposure (16).

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WebAug 1, 2024 · August 1, 2024, 7:30 AM · 5 min read Otonomy, Inc. OTO-313 demonstrated no clinically meaningful improvement versus placebo for primary and secondary … WebNov 2, 2024 · OTO-313 and similar drugs represent a brand new type of tinnitus treatment, where different drug solutions are put into the cochlea with the ultimate goal of changing … WebMar 23, 2024 · OTO-313 and similar drugs represent a brand new type of tinnitus treatment, where different drug solutions are put into the cochlea with the ultimate goal of changing … human centipede adalah