WebNov 10, 2024 · The basis of loading dose calculations involves a drug's volume of distribution (Vd). For phenytoin, a Vd of 0.7 L/kg is used. The following equation is a simple pharmacokinetic equation to estimate a loading dose or resulting serum concentration of … Calculation Basics. The basis of loading dose calculations involves a drug's … WebJun 30, 2015 · Dose rate (mg/hr) = dose (mg) divided by dosing interval (hrs) Maintenance dose rate (mg/hr) = desired peak concentration (mg/L) × clearance (L/hr) Loading dose = desired peak concentration (mg/L) × volume of distribution (L) For drugs not given IV, these doses need to be divided by the bioavailability.
Phenytoin Dosing Calculator and analysis - GlobalRPH
Webphenytoin level may be warranted. Aminoglycosides: Gentamicin or tobramycin Traditional dosing: within 30 minutes before 3rd or 4th dose (pediatrics: 3rd dose) 2-3 doses Trough: < 2 mg/L (< 1 mg/L optimal) Gram positive synergy: within 30 min before 3rd or 4th dose (pediatrics: 3rd dose) 2-3 doses < 2 mg/L (< 1 mg/L optimal) http://file.cop.ufl.edu/pc/PHA5128/5128_case_studies/ans-cs5-01.PDF chhattisgarh holiday calender
fosphenytoin: Dosing, contraindications, side effects, and pill ...
WebMay 20, 2024 · Loading dose: 15 to 20 mg PE/kg IV; infuse at 100 to 150 mg PE/min Maximum infusion rate: 150 mg PE/min Maintenance dose: 4 to 6 mg PE/kg/day in divided … WebLoading Dose Go to Status Epilepticus Calculator 15-20 mg/kg/dose IV Maximum: 1000 mg/dose Maintenance - Initial Starting 12 hours after loading dose 2.5 mg/kg/dose IV/PO BID or 1.7 mg/kg/dose IV/PO TID . Dose may be titrated based on clinical response and/or serum drug monitoring Maximum: 300 mg/24h OR 10 mg/kg/24h WebLoading dose 20 mg/kg, then (by intravenous infusion or by slow intravenous injection) up to 100 mg 3–4 times a day. Adult Loading dose 20 mg/kg (max. per dose 2 g), then (by … gooey python dropdown