Phospho-p53 ser15
WebThe most recent study using analysis of genome-wide binding profiles of phosphorylated p53 has demonstrated that the extent of Ser46 phosphorylation of p53 bound to DNA is higher than Ser15 ... WebPhosphorylated by NUAK1 at Ser-15 and Ser-392; was initially thought to be mediated by STK11/LKB1 but it was later shown that it is indirect and that STK11/LKB1-dependent phosphorylation is probably mediated by downstream NUAK1. It is unclear whether AMP directly mediates phosphorylation at Ser-15.
Phospho-p53 ser15
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WebProduct overview. Phospho-p53 (Ser15) Translocation Assay Kit (Cell-Based) (ab284565) (K966) provides a simple and complete assay in a ready to use format to visualize the … WebExpression levels of p53 and reporters of p53 function (MDM2, p53, Phospho-p53 [Ser15], TIGAR and p21 [CDKN1A]) were examined by western blotting. Results: HPV-positive …
WebBOSTON – A team of researchers from Massachusetts General Hospital (MGH) and Brigham and Women’s Hospital (BWH) has reprogrammed the tumor microenvironment … WebMar 25, 2024 · The E3 ubiquitin protein ligase HERC2 modulates the activity of tumor protein p53 by regulating its oligomerization. J Biol Chem. 2014;289:14782-95 pubmed publisher . …
WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in … WebPhospho-p53 (Ser15) Antibody (PA5-78204) in WB. Western Blot using Phospho-p53 (Ser15) Polyclonal Antibody ( Product # PA5-78204 ). Untreated (–) and treated (+) 293T …
WebA synthetic phospho-peptide corresponding to residues surrounding Ser15 of human phospho p53. Formulation: 1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA: Isotype: Rabbit IgGk: Preparation: Protein A+G: Recommended Usage: 1µg/mL – 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application.
WebThere are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization. p53 has been characterized to play a role in … florida broadband officeflorida broadband internetWebB, The relative protein intensities of p53, phospho-p53 (Ser15), phospho-p53 (Thr55), p21, and survivin as compared with the intensity of α-tubulin. The intensity of each band was quantified using Quantity One software. Data are means ± SD, n = 3. The experiments were conducted in triplicate. great universities for businessWebPhospho-p53 (Ser15) (16G8) Mouse mAb detects endogenous levels of p53 only when phosphorylated at serine 15. The antibody does not cross-react with p53 phosphorylated … florida broadband planWebApr 29, 2004 · Indeed, doxorubicin-induced p53 phosphorylation on Ser15 residue in both MCF7 and MCF55a cells (Figures 3a, b and 5b), and this p53Ser15 phosphorylation was not affected by suppression of ERK2 or ... florida broadleaf mustard green seedsWeb67826-1-Ig targets Phospho-P53 (Ser15) in WB, FC, ELISA applications and shows reactivity with Human samples. Background Information TP53, also known as P53 and NY-CO-13, belongs to the p53 family and has 9 isoforms. In SDS-Page, the observed molecular weight is about 53 kDa. great universitiesWebPhospho-p53 (Ser15) Antibody (MA5-15229) in ICC/IF. Immunofluorescence analysis of Phospho-p53 (Ser15) was performed using 70% confluent log phase HCT116 cells … florida broadband office mapping