WebJan 30, 2024 · Sometimes, sharp pain in the right upper quadrant can signify a serious medical condition. In most cases, people have developed gallstones when they experience excruciating pain after eating a large meal. This condition occurs when there’s excessive cholesterol in the bile. Liver problems can also cause pain near the right rib cage. WebMay 19, 2024 · Signs and symptoms that a person may exhibit if they are in pain: Facial grimacing or a frown Writhing or constant shifting in bed Moaning, groaning, or whimpering Restlessness and agitation Appearing …
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